FORMULATION AND EVALUATION OF HERBAL COUGH SYRUP

Anu Kaushik*

ABSTRACT

In recent years there is a spurt in the interest regarding survival of Ayurvedic forms of medication. In the global perspective, there is a shift towards the use of medicine of herbal origin, as the dangers and the shortcoming of modern medicine have started getting more apparent, majority of Ayurvedic formulation are prepared from herbs. Syrup is very popular dosage form of cough and cold medications, ease of patient compliance. The objective of this study is to develop a polyherbal cough syrup and evaluate the physicochemical parameter along with turbidity/ homogeneity were compared with the changes in accelerated stability testing. Quality of final herbal syrup was evaluated with the parameters: pH, density, total solid content. Three batches were formulated with simple syrup 40%, 50%, 60% w/v .as sugar base. All the batches were evaluated for physicochemical parameters, colour, odour, taste, spec. gravity, pH, total solid content. i.e. Specific gravity (1.24 – 1.36), pH (4.8- 5.0), solid content(37-56.75%). The formulated batches under gone stability studies and microbial test, no turbidity were observed for three months studies and no microbial growth were seen. All the batches assure the reproducibility and each parameter were complying with specifications.

Keywords: Quality of final herbal syrup was evaluated with the parameters: pH, density, total solid content.