( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57



Dipankar Ghara, Rajaram Mohapatra*, Soham Mandal, Anjushree Purkait, Parag Ghosh, Binaya Kumar Sethy, Sujayita Mazumder and Anamika Saha


Peptic ulcer is a chronic disease that affects about 10% of total population in the world. Ulcer is an acid-induced lesion of the gastrointestinal (GI) tract which causes an open and painful sore. Peptic ulcers are mainly arisen in stomach or proximal duodenum.[1] Helicobacter pylori (H.Pylori) play an important role in the pathogenesis of peptic ulcer mainly involving antral mucosa or muscularis propria. The human immune system is incapable to eradicate this infection without affecting the antibody production. As a result, the bacterium can consequently lead to form a chronic active gastritis. It may cause an increase in gastrin production or more frequently gastrin formation may hamper. Gastrin increase the production of gastric acid formation and H.Pylori increases the gastrin formation by colonization. These excess amounts of acid formation lead to erosion of mucosal membrane, which leads to formation of ulcer. The use of non-steroidal anti-inflammatory drugs (NSAIDs) are the another major causative reason for ulcer formation. The gastric mucosa itself protects with a layer of mucus from gastric acid. Mucus secretion is inspired by the prostaglandins. Cyclooxygenase is the main source for production of prostaglandins. Which function is blocked by the using of NSAID .The duodenal ulcers has decreased significantly in last 30 years, while the incidence of gastric ulcer is increase in last few years due the use of NSAIDs. Younger patient with ulcer treated with antacids or H2 antagonists. Patients those are taking nonsteroidal anti-inflammatory also prescribed with prostaglandin analog to prevent peptic ulcer.

Keywords: .

[Full Text Article]



  • New Issue Published

    Its Our pleasure to inform you that, EJPMR 1 September 2023 Issue has been Published, Kindly check it on


    SEPTEMBER issue has been successfully launched on 1 SEPTEMBER 2023.

  • EJPMR New Impact Factor

    Its our Pleasure to Inform you that EJPMR Impact Factor has been increased from  5.804 to 6.222, due to high quality Publication at International Level

  • Index Copernicus Value

    EJPMR Received Index Copernicus Value 79.57, due to High Quality Publication in EJPMR at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.


  • Article Invited for Publication

    Article are invited for publication in EJPMR Coming Issue

Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database