AN OBSERVATIONAL STUDY ON DRUG UTILIZATION PATTERN IN CHRONIC KIDNEY DISEASE PATIENT USING ANTIHYPERTENSIVE DRUGS IN A TERTIARY CARE TEACHING HOSPITAL.

Dr. Vikneswari A.*, Safthar Ahammed P. P., Dr. Vishwas ATL and Dr. Suresha B. S.

ABSTRACT

Chronic kidney disease (CKD) is a major public health issue and widely prevalent non-communicable disease in India. hypertension can be a cause or a consequence of chronic kidney disease. CKD patients require to take medications for a lifelong period, which makes it very important to study the prescribing trends on a regular basis, there is a strong relationship between Hypertension and CKD. Methodology: this is a prospective, cross-sectional study. Result: total of 110 patient records were analysed. Demographics shown males (60%) and females (40%) more patients were in the age group of 46-65 year (45%). CKD patients of stage 5 (87%), stage 4 patients (13%), and the patients in other stages were (0%). 146 anti-hypertensive drugs prescribed majority of patients prescribed CCB (43%). The co-morbidity, majority of patients were suffering anemia (76%). Among total study subject, 30 drug interaction are found and minor drug interactions are counted 18 (60%), moderate drug interaction counted 10 (33%), and major drug interactions counted 2 (7%). Maximum no of drugs was prescribed in generic name (90%). Conclusion: Clinical pharmacist plays an important role in the selection of drugs for treatment of CKD with hypertension otherwise leads to increase mortality and morbidity. Improving medication adherence, patient counselling and dietary recommendations helps the patient to increase good therapeutic outcomes.

Keywords: Chronic kidney Disease, Antihypertensive, Drug Utilization Pattern.