CONVENTIONAL AND MICROWAVE ASSISTED SYNTHETIC METHOD OF 1,3,4 THIADIAZOLE DERIVATIVES-A REVIEW

Shilpa Sathish K.*, Shalima N. K., G. Babu, Biju C. R., Adhiti Sibi, Ashitha Sivadas K.

ABSTRACT

The primary techniques used to synthesis the novel compounds comprising 1,3,4-thiadiazole derivatives using both conventional and microwave-assisted methods are highlighted in this review (cyclization, diazotization and etherification respectively). Thiadiazole is a five-membered heterocyclic organic molecule with one sulphur and two nitrogen atoms. With a wide range of physiologically active properties, 1,3,4-thiadiazoles rank among the most active chemical classes.

Keywords: Thiadiazole derivatives, microwave assisted synthesis, one pot synthesis.