EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia , 

 ISSN 2394-3211

Impact Factor: 7.065

 ICV - 79.57

Abstract

A CROSS-SECTIONAL STUDY OF ASSOCIATION OF INTRARENAL VASCULAR RESISTANCE WITH BIOCHEMICAL PARAMETERS IN PATIENT WITH TYPE-1 DIABETES MELLITUS

*Dr. Shyam Sunder Hembram, Dr. Saurav Das, Dr. Khokan Mandi and Dr. Ram Chandra Bhadra

ABSTRACT

Background: The present study aims at identifying early vascular changes which may help to identify children with early progression of diabetic nephropathy by using non-invasive doppler study and if clinically useful information is obtained it may be useful in follow up for the treatment. Materials and methods: This cross-sectional study was done in a tertiary care hospital in India. A total of 120 samples were taken in which 60 were patients with type 1 diabetes mellitus and 60 were age, sex and BMI matched healthy controls. The doppler parameters like renal Resistivity index, Peak systolic velocity and End diastolic velocity and various blood parameters were evaluated and compared between the cases and controls. Results: Peak systolic velocity of the cases was significantly higher than the controls (p=0.037). End diastolic velocity of cases was lower than the controls. Resistivity index of cases was significantly higher than the controls (p=0.001). Among the blood parameters, HbA1C, ACR, GFR, triglyceride, LDL and HDL were found to vary significantly between cases and controls (p<0.05). Conclusion: The doppler parameters like renal Resistivity index, Peak systolic velocity and End diastolic velocity can be used as potential tools to identify early progression of diabetic nephropathy in children.

Keywords: Diabetic nephropathy, Doppler, Resistivity index, Peak systolic velocity and End diastolic velocity.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia