EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia , 

 ISSN 2394-3211

Impact Factor: 7.065

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Abstract

A RETROSPECTIVE ANALYSIS OF PLASMA SEX HORMONE LEVELS IN MALE AND FEMALE PATIENTS WITH ANDROGENETIC ALOPECIA.

Shankar Nath, Zhang Zhiying, Chen Ting, Luo Na, Du Mingyin, Song Jiquan* and Xie Jun*

ABSTRACT

Introduction: Androgenic alopecia (AGA) is characterized by progressive scalp hair loss. It is responsible for hair loss in both men and women, often manifesting in the 3rd and 4th decades of life. AGA pathogenesis is linked to hormonal imbalance and genetic predisposition. In practice determination of serum levels of sex hormone, is prerequisite for AGA diagnosis. Here, we retrospectively examined the serum levels of five sex hormones in patients with androgenic alopecia, compared to levels in those without alopecia. Materials and Methods: A retrospective observational study was conducted at Zhongnan Hospital of Wuhan University from January 2022 to February 2023. Serum levels of five sex hormones were analyzed in androgenic alopecia patients and non-alopecia controls. Results: A total of 78 cases, and 94 controls were analyzed. 47 (60.2%) of the cases were males, and the mean (±SD) age were 31.84±5.42 vs 27.23±7.05 years for the cases and controls respectively. 55.1% of cases had family history of alopecia. In males, Testosterone, and Estrogen were all significantly higher in cases than controls, (all p < 0.05), while Follicle stimulating hormone, and Luteinizing hormone were lower in cases than controls (all p < 0.05). In females, Testosterone and Prolactin were significantly higher in cases than controls (all p < 0.05), while Follicle stimulating hormone, and estrogen were significantly lower in cases than controls (all p < 0.05). Conclusions: High levels of Testosterone were observed in the alopecia patients compared to non-alopecia individuals in both genders, and this could be linked to the alopecia.

Keywords: Androgenic; Alopecia; Sex Hormones; Testosterone; Prolactin.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia