EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia , 

 ISSN 2394-3211

Impact Factor: 7.065

 ICV - 79.57

Abstract

A REVIEW ON TARGETED DRUG DELIVERY SYSTEM

Sri Ranga T., Siddalinga Swamy PM*, Chandana CM, Suchitra TS, Thanmayi MO, Anjali KK and Vijayalakshmi MA

ABSTRACT

New form of drug delivery system is drug targeting. The goal of the drug targeting is to deliver the drug to that targeted site of action without releasing the drug at non targeted site or without damaging other tissues/organs/cells. It has more advantages over conventional drug delivery system like low side effects, improvement of pharmaceutical activity and reduction of administered dose. The main reason of the targeted drug delivery system is to provide good pharmacological therapeutic agents for diseased organs without harming healthy tissues. Cancer treatment with chemotherapeutic agents have more side , targeted drug delivery system serve a purpose to reduce those side effects. various drug carrier which can be used in this advance delivery system are soluble polymers, biodegradable, microsphere polymers (synthetic and natural), neutrophils, nanoparticles, lipoproteins, liposomes, micells, niosomes, these carriers maintain and transport the loaded drug to the pre-selected organ. Drug targeting have a different mechanisms such as passive targeting, inverse targeting, active targeting, physical targeting, ligand-mediated targeting, dual targeting and double targeting. Targeted drug delivery system is useful for delivering the therapeutic agent to a particular site of action without causing any virulent effect to other organs.[2] GOAL OF TDDS To prolong, localize target and have a protected drug interaction with a diseased tissue.[³]

Keywords: Therapeutically active drug, drug delivery, drug targeting, chemotherapeutic agents, therapeutic action.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia