EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia , 

 ISSN 2394-3211

Impact Factor: 7.065

 ICV - 79.57

Abstract

PRIMARY HYPERPARATHYROIDISM: CASE REPORT OF ADVANCED DISEASE

Dr. Mahesh Brungi*, Dr. Prathap B., Dr. Abdul Gafoor P. M., Dr. Nazneen Abdul Kader, Dr. Ajith T. Abraham

ABSTRACT

Primary hyperparathyroidism is a condition characterized by hyper function of one or more parathyroid glands leading to uncontrolled secretion of parathyroid hormone. The most common cause of primary hyperparathyroidism is parathyroid adenoma, followed by hyperplasia and carcinoma in 1 to 2% of cases. Patients most commonly presents with symptoms of hypercalcemia which occurs due to increased resorption of calcium from bones, increased absorption of calcium in bowels and decreased urinary elimination of calcium. Clinically patient presents with multiple bone pain, loss of appetite, nausea, vomiting, loss of weight, constipation, depression and symptoms of nephrolithiasis. Diagnosis is mainly based on the clinical presentation and serum levels of calcium, phosphorus, alkaline phosphatase, albumin and parathormone levels, ultrasonography of neck with FNAC studies and sestamibi scan for parathyroid gland. Here we are reporting a case of a middle aged woman with primary hyperparathyroidism who presented to us with advanced disease. After thorough clinical, laboratory and radiological evaluation, primary hyperparathyroidism due to adenoma in the left parathyroid lobe was diagnosed for which she underwent focused parathyroidectomy. Intra op frozen section confirmed the adenoma. After symptomatic and supportive therapy, she was completely normal and resumed all her daily activities.

Keywords: Primary Hyperparathyroidism, Parathyroid adenoma, Brown tumour, Sestamibi scan.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia