EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia ,

ISSN 2394-3211

Impact Factor: 7.065

ICV - 79.57

Abstract

A RARE CASE OF TOPICAL CLOBETASOL-INDUCED HYPOCORTISOLISM

Archana Rajan*, Rintu Mary Roy, Sharon Susan Raj, Philip Finny and Swetha Reba Mathews

ABSTRACT

Clobetasol is a very active synthetic glucocorticoid. Adverse drug reactions (ADR) associated with clobetasol include gastrointestinal disorders, weight gain, hypersensitivity reactions, adrenal insufficiency (hypocortisolism), Cushing syndrome, etc. Among these, hypocortisolism is one of the most important adverse reactions. A case report of a 56-year-old female patient who was prescribed topical clobetasol and presented with features suggestive of hypocortisolism, namely, fatigue, tiredness, and sudden increase in body weight. This case report serves as a reminder for healthcare professionals regarding ADR of Clobetasol and on the need of healthcare education to patients when topical steroids are being prescribed.

Keywords: Clobetasol, Glucocorticoid, Hypocortisolism, HPA axis suppression.

[Full Text Article] [Download Certificate]