EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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ISSN 2394-3211

Impact Factor: 7.065

ICV - 79.57

Abstract

COMPARATIVE EFFICACY OF HERBAL GEL ON ORAL HYGIENE AND MOUTH FRESHNESS: A DOUBLE-BLIND CONTROLLED STUDY

Dr. Sonia Datta*, Amit Sirdesai, Dr. Prasun Bandyopadhyay and Jyoti Singh

ABSTRACT

Background: Halitosis or bad breath is an oral health condition characterized by unpleasant odours emanating consistently from the oral cavity. The origin of halitosis may be related both to systemic and oral conditions, but a large percentage of cases, about 85%, are generally related to an oral cause. The causes include certain foods, poor oral health, improper cleaning of dentures, dry mouth, tobacco products and medical conditions.[1] Aim: A Clinical study was conducted to evaluate the efficacy of Herbal Gel toothpastecomprising of Zinc Sulphate (GandhakamleeyaYasada), Herbal extract and blend of essential oils for an oral malodour, Gingivitis Index(GI) and Plaque Index(PI)and Oral Hygiene Index evaluation study. Material and Method: A double blind, three-arm, randomized clinical study involving105 subjects (18-45 years) with complaints suggestive of plaque induced gingivitis,malodour and other set inclusion criteria;was conducted by randomly assigning the subjects to one of three study groups (35 each). Result: Results showed that test product Herbal Gel was 2 times and 4 timesstatistically significant in controlling oral malodourwhen tested against Control Gel and Control toothpaste respectively. Test product Herbal Gel was also found effective to reduce gingival index and plaque index and showedimprovement of oral hygiene index which was statistically significant v/s baseline and v/s control test products. Test product Herbal Gel was found to statistically significant in reducing oral malodour with single use, post 4 weeks of regular usage and even after 12 hours brushing post 4 weeks regular use. Conclusion: It can be concluded that test product Herbal Gel wasfound significantly effective in comparison to the marketed products on clinical parameters GI, PI, OHI-S and Oral Malodour.

Keywords: OralMalodour, Gingivitis, Plaque, Toothpaste, Herbal gel, Ayurvedic Zinc sulphate.

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