EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia , 

 ISSN 2394-3211

Impact Factor: 7.065

 ICV - 79.57

Abstract

SCOPE OF CELL SHEET ENGINEERING IN PERIODONTICS – A NARRATIVE REVIEW

*Dr. Anusha D., Dr. Suchetha Aghanashini, Dr. Sapna Nadiger, Dr. Darshan Basavaraj Mundinamane, Dr. Apoorva Sokke Mallikarjunappa and Dr. Vinodhini

ABSTRACT

Tissue engineering including stem cell therapy is an emerging technique used for the regeneration of lost tissues in Medicine and Dentistry. Tissue engineering aims to engineer tissues by selecting optimal concentration of cells which acts as biological mediators and selectively enhance the chances of increase in cell matrix in periodontal defects. It helps in regeneration but has drawbacks such as isolating the correct type of cells and preparing a conducive environment for their growth. To overcome the limitations of present-day regeneration techniques, cell sheet engineering is gaining popularity. Cell sheet engineering offer several advantages over conventional stem cell engineering such as avoiding host inflammatory response, creation of extracellular matrix with intact cell-to-cell junctions, and escaping enzymatic degradation as these are thermo-responsive. Cell sheets appear to have a promising role in periodontics due to their ability to regenerate a variety of tissues such as gingiva, enamel, dental pulp, periodontal ligaments cells, cementum, alveolar bone, peri-implant tissue, and sections of the temporomandibular joint. In this review, tissue reorganization by using cell sheet engineering will be discussed along with sources of cell sheets, steps in preparation, and types of cell sheets both used in-vivo/in-vitro studies.

Keywords: Periodontics, Regeneration, Stem Cells.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia