ROLE OF “STEM CELL” IN DIFFERENT DISEASES & THERAPY

Gusinge P. M.*, Phoke S. V., Hatkar A. D., Rawat S. S. and Mahajan C. C.

ABSTRACT

Stem cells are defined as cells that have clonogenic and self-renewing capabilities and differentiate into multiple cell lineages. Stem cells are found in all of us, from the early stages of human development to the end of life. Stem cell Therapy is emerging as a potentially revolutionary new way to treat disease and injury, with wide-ranging medical benefits. Stem Cell research presents many ethical and scientific questions as well as future challenges. Stem cells are basic cells of all multicellular organisms having the potency to differentiate into wide range of adult cells. In recent years, stem cell therapy has become a very Promising and advanced scientific research topic. Stem cells are unspecialized cells that develop into the specialized cells that make up the Different types of tissue in the human body. In particular, mesenchymal stem cells (MSCs) have been successfully tested in some clinical trials in patients with COVID-19. The encouraging results positioned MSCs as a possible cell therapy for COVID-19. In this paper the goal is Evaluation of cell therapy in treatment of Parkinson‘s disease, Amyotrophic lateral sclerosis, Alzheimer, Stroke, Spinal Cord Injury, Multiple Sclerosis, Radiation Induced Intestinal Injury, Inflammatory Bowel Disease, Liver Disease, Duchenne Muscular Dystrophy, Diabetes, Heart Disease, Bone Disease, Renal Disease, Chronic Wounds, Graft-Versus-Host Disease, Sepsis and Respiratory diseases. It should be Mentioned that some disease that are the target of cell therapy are discussed in this article.

Keywords: Stem cells, embryonic stem cells, adult stem cells, umbilical cord blood, spinal cord stroke, transplants, pluripotency, Alzheimer‘s disease, injury, regerative medicine.