EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

BULLOUS PEMPHIGOID: A CLASSICAL CASE REPORT MANAGED WITH PULSE THERAPY

Dr. M. A. Lavanya*, Dr. Nirumal Rakkesh M. and Dr. Naveen K. Erusappan

ABSTRACT

Bullous pemphigoid is an autoimmune blistering disorder that typically presents in elderly patients as pruritic tense subepidermal blisters. It presents clinically with diffuse eczematous, pruritic, urticaria-like lesions, with the later appearance of tense bullae or blistering lesions typically filled with clear fluid. It primarily affects elderly individuals with an average age of onset being 65 years.Bullous Pemphigoid (BP) can be diagnosed clinically with a high index of suspicion with the aid of skin biopsy and histology.[1] A 64 year old female patient with known comorbidities of Systemic hypertension and type2 diabetes mellitus, presented with complaints of multiple vesicles all over the body, pain and burning sensation all over the body since 20days. She was initially treated in nearby clinic for the same. She had past surgical history of lump excision on scalp few years back. On physical examination, some of the lesions had ruptured and were both pruritic and painful. Baseline blood investigations done. Skin biopsy was done revealed Bullous Pemphigoid. Dermatologist opinion was sought in view of painful blisters on she advised for 3 days cycle Pulse therapy. The pathogenesis of BP is complex and its treatment and management still represents a challenge due to higher frequency of several comorbidities in this group of patients which may leads to tolerance to Bullous Pemphigoid treatments. Hence an early diagnosis and a prompt treatment are mandatory to reach better clinical outcome.The aim of this case report is to present a classic case of this condition, to highlight an awareness of differing treatment options, and to advocate referral to a dermatologist given its potential severity.

Keywords: Bullous Pemphigoid, Pulse therapy, Autoimmune-disease.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database