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An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57



S. Anjanikar and S. Chandole*


3-acetyl 4-Hydroxy quinolin-2-one and substituted pyridine containing Schiff bases were used to synthesize Cu (II) and Zn (II) complexes. The Schiff base ligands utilised for complex formations are 4-hydroxy-3-(1-(pyridin-2-ylimino)ethyl)quinolin-2(1H)-one (L1), 4-hydroxy-3-(1-(pyridin-3-ylimino)ethyl)quinolin-2(1H)-one (L2), 4-hydroxy-3-(1-(pyridin-4-ylimino)ethyl)quinolin-2(1H)-one (L3) and 3-(1-((5-chloropyridin-2-yl)imino)ethyl)-4-hydroxy quino- lin-2(1H)-one (L4). The synthesised metal complexes were characterized by their elemental anal- ysis, magnetic moment, molar conductance along with electronic, thermal, infrared spectral analysis. Cu(II) and Zn (II) complexes of ligand (L3) were subjected for their XRD Study. On the basis of magnetic, XRD and spectral studies octahedral geometry is assigned to Cu (II) Complexes while Zn (II) Complexes possess tetrahedral geometry. In vitro biological screening effects of the synthesized complexes were tested for their antibacterial activity by Agar well diffusion method and antifungal activity by the poison plate method. For antibacterial activity the bacterial species used were Bacillus subtilis, Escherichia coli, Salmonella typhi, and Staphylococcus aureus while fungal species used were Aspergillus flavus, Penicillium chrysogenum, Aspergillus niger and Fusarium moneliforme.

Keywords: 3-acetyl 4-Hydroxy quinolin- 2-one, Schiff Bases, Metal Complexes, Spectral Analysis, XRD Studies, Antimicrobial Activity.

[Full Text Article]



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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database