EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

PHARMACOGNOSTIC EVALUATION AND ICP-MS BASED METAL DETECTION IN PERGULARIA DAEMIA (AERIAL PART)

Anitha John*, A. Sakkeena, K.C. Manju, B. Neethu Kannan, V.L. Reena, S. Selvarajan and
A. Kanagarajan

ABSTRACT

The quality control standards of various medicinal plants used in indigenous systems of medicine are significant nowadays in view of the commercialization of herbal formulations. The major limitation of herbal medicines is the lack of standardization. The present study attempts to evaluate the identity, degree of purity and authenticity of the medicinal plant, Pergularia daemia (Forssk.) Chiov. It is a perennial twinning vine belonging to the family, Apocynaceae. The plant material was collected from three different geographical areas. Various pharmacognostic tests like anatomy, powder microscopy, physico-chemical and chromatography were executed by standard methods to evaluate the plant materials. High Performance Thin Layer Chromatographic (HPTLC) studies of the alcohol extracts were performed. Metal content present in these three accessions of the plant materials was also determined by employing ICP-MS. The evaluation of the physical constants of the drug is an essential parameter in detecting adulteration or improper handling of drugs. Pharmacogonstic parameters established the identity, purity and quality of the aerial part of Pergularia daemia. HPTLC fingerprint patterns unravelled the presence of various phytochemical constituents. These results help in the identification and standardization of the drug. The determined element concentrations were within the international safety limits. This makes the plant acceptable for human and animal consumption at nutritional as well as medicinal levels.

Keywords: Pergularia daemia, microscopy, physico-chemical analysis, HPTLC, ICP-MS.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database