EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

DIAGNOSTIC ACCURACY OF CT HOUNSFIELD UNIT FOR DETECTION OF CALCIUM STONES IN PATIENTS WITH RENAL STONE DISEASE

*Dr. Mudassar Saeed Pansota (MS Urology), Dr. Fariha Mumtaz (FCPS Radiology), Dr. Mubasher Saeed Pansota, Dr. Muhammad Burhan Barkar (MS Urology), Dr. Muhammad Shahzad Saleem (FCPS)., Dr. Mumtaz Rasool (FCPS).

ABSTRACT

Introduction: Different radiological investigations are used to evaluate renal stones and among all, non-contrast-enhanced computer tomography (CT) provides the highest level of diagnostic accuracy with low radiation exposure for urinary stones. Hounsfield unit is linear transformation of original linear attenuation coefficient measurement into one in which the radio-density of distilled water at standard pressure and temperature is defined as zero Hounsfield unit. Materials & Methods: A total of 201 patients of both genders (Male and Female) with age 15-60 years presenting with renal stones of any size undergoing percutaneous nephrolithotomy were included. Pregnant females, claustrophobia, young age and morbid obese were excluded. Non-contrast Computerized Tomographic scan (CT scan) was performed. Using GE-128 Slice and Hounsfield Unit was determined. Patient were undergone percutaneous nephrolithotomy and extracted stone was subjected to chemical analysis. Results: In CT positive cases, 95 were true positive and 08 were false positive. While in CT negative patients, 91 were true negative and 07 were false negative. Overall sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy of CT Hounsfield unit for detection of calcium stones in patients with renal stone disease taking stone chemical composition as gold standard is 93.14%, 91.92%, 92.23%, 92.86% and 92.54% respectively. Conclusion: This study concluded that the diagnostic accuracy of CT Hounsfield unit for detection of calcium stones in patients with renal stone disease is very high.

Keywords: Urolithiasis, calcium oxalate, computed tomography.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database