CORRELATION BETWEEN LEVELS OF SERUM 25(OH)D AND LIPID PROFILE COMPONENTS IN STUDY POPULATION

Purabi Barman*, Afsana Akhter, Monika Roy, Sushanta Kumar Barman, Muhammad Ehasun Uddin Khan, Muhammad Anamul Hoque and Manindra Nath Roy

ABSTRACT

Background: Since the prevalence of vitamin D deficiency is high in some countries and the trend of hypertension and obesity is increasing, this study aimed to investigate the serum level of vitamin D and explore its correlation and association with obesity, blood pressure, and lipid profile. Our hypothesis is that serum vitamin D levels are associated with risk factors for cardiometabolic disease such as hypertension. Objective: To find out the correlation between levels of serum 25(OH)D and lipid profile components in study population. Methods: This cross-sectional analytical study was carried out in the Department of Biochemistry of Sir Salimullah Medical College & Mitford Hospital, during July 20- June 21. 100 female subjects aged belong to 19-29 yrs were selected by purposive sampling. Among them 50 women were obese (BMI ≥25 kg/m²) and 50 women were non-obese (BMI< 25 kg/m²). Initial evaluation was done by history taking and anthropometric indices were measured. Results: Vitamin D had no significant (p>0.05) relationship (r=0.032,p=0.755) with age. Vitamin D had a significant inverse relationship (r=-0.264,p=<0.01) with BMI. It was also inversely related to WC (r=-0.209, p=<0.05) which was significant (p<0.05).Vitamin D had a significant (p<0.05) inverse relationship with WHR, TC, TAG and LDL-C (r=-0.246, -0.299, -0.276, -0.257, p= 0.014, 0.003, 0.005, 0.010 respectively). Conclusion: Obese young women have low serum vitamin D level. There is a significant correlation between levels of serum 25(OH)D and lipid profile components in young women.

Keywords: Obesity, Young adults, Vitamin D deficiency.