( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57



Dharyappa Teli*, Dr. R.B. Kotnal and Sangappa Teli


When the viable solvents businesses launched penicillin, in the establishment of 19th century invented by Alexander Fleming, a major reduce in the number of deaths caused by bacterial infections has been confirmed. Optimists have even noticed an end to the period of bacterial diseases. However, too frequent, and frequently improper, applications of antibiotics have resulted in the development of drug resistant bacteria such as methicillinresistant Staphylococcus aureus (MRSA), WHO generated a list of priority pathogens to focus the development of new antibacterial drugs against; MRSA ranked as a high priority. Unfortunately, the development of new antibacterial drugs has progressively declined since the 1980s. In my research work novel derivatives of Quinoxaline obtained from ortho phenylene diamine and pyruvic acid gives 3,6-methyl quinoxaline-2(1H)-one [DR-I] it was treated with phosphorous pentasulphide gives 3,6-methyl quinoxaline-2(1H)-thiol [DR-II] which is converted into resultant compound derivatives of 2,6-methyl-3-[(3-nitropyridin-2-yl) sulfonyl] quinoxaline (DRIIA- IIF). All the compounds synthesized were confirmed by spectral data and evaluated for their methicillinresistant Staphylococcus aureus (MRSA) activity Vancomycin was used as standard. The compounds DR-IIA and DR-IID have shown good activity and remaining shows poor activity against bacteria.

Keywords: Quinoxalines, Antibacterial Activity, Vancomycin, Methicillin-Resistant Staphylococcus aureus (MRSA).

[Full Text Article]




    December issue has been successfully launched on December 2023.

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia