EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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ISSN 2394-3211

Impact Factor: 7.065

ICV - 79.57

Abstract

EFFECT OF WHOLE CELL (WC) AND OUTER MEMBRANE PROTEIN (OMP) VACCINES ON PROTECTION OF CATLA CATLA AGAINST STAPHYLOCOCCOSIS OF STAPHYLOCOCCUS AUREUS

S. Mumtaj* and G. B. Brindha Devi

ABSTRACT

Immunoproteomic vaccines provide protection against bacterial infections in fish aquaculture and the vaccines are getting popular due to its long lasting immunity, safety and low cost. In this study we used Whole cell – Formalin Killed (WC) and Outer Membrane Protein (OMP) of S.aureus as a vaccine to provide protection against staphylococcosis disease in fish Catla catla. We used the extract of Asparagus racemosus as an adjuvant in the vaccine preparation. Survival of the vaccinated fishes (30 and 60 days’ post vaccination (dpv)), were evaluated after challenge with virulent S.aureus. The results showed that the relative percentage of survival in the catla fish groups vaccinated by Outer Membrane Protein (OMP) vaccine with adjuvant were significantly higher than that the other types of vaccines (84%).

Keywords: Staphylococcus aureus, Catla catla, Asparagus racemosus, WC and OMP.

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