( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57



Dr. Babul Chandra Saha*, Dr. Khatun E Zannat, Dr. Afia Afrin, Dr. Muhammad Moinul Alam Talukder, Dr. Jakia Binte Joynal


Background: Multidrug-resistant tuberculosis (MDR-TB), which is defined as resistance to at least rifampicin and isoniazid, and rifampicin-resistant tuberculosis (RR-TB) have emerged as a significant barrier to TB control across the world. Objective: In this study our main goal is to evaluate rifampicin resistance in mycobacterium tuberculosis using GeneXpert in tertiary Medical College and Hospital. Method: This cross-sectional study was done at tertiary medical college and hospital at Dhaka from April 2021 to April 2022, where 60 clinically suspected or documented tuberculosis cases were selected as a sample population. Results: More than half of the study's patients were men, and most (52%) were in their 20s and 30s. There was a significant history of smoking in almost 40% of the patients. Thirteen percent of patients started therapy more than 30 days late, and in eight percent of instances, the treatment was not completed. Results reveal that 5 percent of Rifampicin (RIF) resistant cases discovered by GeneXpert MTB/RIF were phenotypically validated as DR strains, indicating that drug resistance is rather common. Not only that, but 66.7% of the resistant instances were discovered to be male. Conclusion: Our research shows that the spread of medication resistance across TB strains is a major problem for global TB elimination efforts. The excellent sensitivity and specificity of Xpert MTB/high RIF for the identification of RIF resistance validate its use as a screening tool for RIF resistance. Therefore, it would greatly benefit treatment regimen adjustments and DR TB containment if labs routinely tested for DRTB using molecular techniques.

Keywords: Drug resistance (DR), tuberculosis (TB), multiple drug resistance (MDR).

[Full Text Article]



  • New Issue Published

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    SEPTEMBER issue has been successfully launched on 1 SEPTEMBER 2023.

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database