EVALUATION OF ANTI-INFLAMMATORY ACTIVITY OF ELAGESIC LINIMENTS ON EXPERIMENTAL ANIMAL

Sachin Korde*, Jugal Kishor Vyas, Vivek Paithankar and Anjali Wankhede

ABSTRACT

Objective: The main objective of the present research is to evaluate the anti-inflammatory activity of elagesic liniment on Wistar rats. Materials and methods: The elagesic liniment formulation were purchased, identified and Authenticated by Arpita Pharma, Nashik. After evaluation of various physical parameters like globule size, pH, viscosity, were selected for pharmacological evaluation. These formulations were subjected for evaluation of anti-inflammatory effect using carrageenan induced paw edema method. Results: The edema in paw was measured using plythesmometer. The inhibition obtained with liniment was 63.15%, oedema which was induced by carrageenan on sub-plantar administration when compared with untreated control groups. When compared to that of the standard group which clearly indicates the anti-inflammatory activity of elagesic liniment. Conclusion: Thus from the present study, it was concluded that the elagesic liniment shows significant anti-inflammatory activity.

Keywords: Elagesic liniment, anti-inflammatory.