EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

NANOEMULGEL – AN INNOVATIVE APPROACH FOR TOPICAL DELIVERY USING HIGH ENERGY METHOD

Dr. Abdul Mannan, Arkaan Qamar Abbas, Uzma Amatul Aleem*

ABSTRACT

As an emerging transdermal delivery tool, nanoemulgel, has proved to show astonishing upshots for the lipophilic drugs over other formulations. The goal of this review is to formulate the nanoemulsion using microfluidizer to achieve better stability of formulations and to evaluate and report the current potential and future scope of nanoemulgel formulation for becoming an effective delivery system for poorly water-soluble drugs. Lipophilic drugs can be easily incorporated and the skin permeability of the incorporated drugs can be increased in several folds due to the finely distributed oil droplets in gel phase. Concurrently, it can be targeted more specifically to the site of action and can avoid first pass metabolism and aid the user from gastric/systemic incompatibilities. The nanoemulgel drug delivery system is a formulation related intervention to enhance drug absorption and therapeutic profile of lipophilic drugs. An emerging trend has been noticed in recent years in the use of nanoemulgel due to the better acceptability of the formulation to the patients due to their non-greasy nature which favours user compliance, convenience, spreadability, and easy applicability and good therapeutic and safety profile. Despite having few drawbacks, nanoemulgel formulation can be considered as potential and promising candidates for topical delivery of lipophilic drugs in the future.

Keywords: Nanoemulgel; Nano emulsion; Topical drug delivery; High Energy Method.


[Full Text Article]

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  • New Issue Published

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database