A REVIEW ON COVISHIELD VACCINE FOR COVID-19

Sajitha P.*, Pavithra S., Kavitha M. and Akshara S. P.

ABSTRACT

A Coronavirus (SARS-CAOAV-2) was emerged in wuhan, china in late December 2019. The ICTV named the virus as SARS-CoV-2 and the disease as COVID-19. The disease can spread through both direct means or by indirect contact. The most common symptoms are fever, chills, dry cough, fatigue, shortness of breath, head and muscle pain, weight loss, etc. The COVID-19 disease can be diagnosed by RT-PCR assay and by the serological evaluation of IgM, IgG antibodies. The ChAdOx1 nCoV-19 vaccine (AZD1222) was developed at Oxford University. The COVISHIELD vaccine was manufactured in the Serum Institute of India. Covishield vaccine was used for the prevention of the COVID-19. Its efficacy rate is 81.3%. The following study elaborates about the ingredients of vaccine, dose, route of administration, mechanism of action and pharmacodynamics of the vaccine. Once the vaccine is injected, it instructs the human cell to produce immunity against the coronavirus. The side effects of the vaccine and tips to reduce the side effects were elaborated in the study.

Keywords: Coronavirus, symptoms, transmission, diagnosis, COVISHIELD, mechanism of action, pharmacodynamics, side effects.