REVIEW OF MECHANISM OF ACTION OF DRUG ABSORPTION THROUGH OLFACTORY REGION
Dr. Ashu Sharma*, Dr. Ravindra Kumar, Dr. Atul Bhardwaj, Dr. Arun Gupta
Nasal route offer a better route for delivery of drugs for local, systemic circulation and central nervous system as it circumvents the first pass metabolism, easy to use, can be used in those patients in which neither intravenous nor the oral route is preferred .This article outlines the relevant aspect of nasal anatomy, histology, physiology and pathways for transportation of nasal drugs transgressed through the olfactory area.
Keywords: Nasal drug delivery system, Mucociliary clearance(MCC),Histology of nose, olfactory epithelium(OE).
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