EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

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Abstract

THE STUDY OF VYASAN (ADDICTION) HETU FOR PATHOGENESIS W. S.R TO ORAL SUBMUCOSAL FIBROSIS

*Dr. Nitesh S. Deotale and Dr. Ujwala V Pawar

ABSTRACT

Lifestyle disorder primarily based on daily habits, Some common disease are ,Alzheimer disease, cancer, arteriosclerosis, cirrhosis, COPD, DM,HTN, etc. They take year to develop caused by factor heat, sound, dust, fumes, smoke. Vyadhi occurred by doshdushti and dhatudourbalya, etiological factor are ahara, vihara, vyasana, manas&aushadhi. Vyasan are of different kinds like alcohol, tobacco pan- guthakha, smoking etc. gutakha and pan masala are widely used because of low cost, easily available, easily handle. On routine observation seen that these vyasan cause OSF. According to ayurveda nidan, doshdushti, dhatudushti, dhatuvikruti (Twak), reversible and irreversible. In OSF it is reversible, cause by vata kapha, 70% of oral cancer are vata kapha, according to modern arecoline(alkaloid) stimulate fibroblast and increase production of collagen by 150%. Oral sub mucous fibrosis is a chronic disease of the oral sub mucosa characterized by inflammation and progressive fibrosis, which has high risk of malignant transformation. It can be prevented by changing lifestyle and sesation of chewing betel nut. The fibrosis can be reversible, By the use of Bhallataka which is anticancerous drug and also vatakaphaghna may be effective in OSF.

Keywords: According to ayurveda nidan, doshdushti, dhatudushti, dhatuvikruti (Twak), reversible, irreversible.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia