EVALUATION OF ANTIDIABETIC ACTIVITY OF URARIA PICTA LEAVES ON EXPERIMENTAL ANIMALS
Irfan Ali*, Dr. Nasiruddin Ahmad Farooqui* and Jiyaul Hak
ABSTRACT
The present work is an effort to look at the effect of Uraria picta leave extract on streptozotocin induced diabetes in Wistar mice. Two groups of streptozotocin persuaded diabetic mice were orally treated through Uraria picta leave extract (150 and 300mg/kg) respectively. The blood glucose level, body mass, Glycosylated hemoglobin, liver glycogen, lipid profile, Antioxidant status were measured at the finish of the study that is after 100 days of Uraria picta leave extract were originate to be significant (p < 0.05) in dropping the blood glucose level, glycosylated hemoglobin, triglyceride, cholesterol, LDL, VLDL, HDL, blood urea, lipid profile, while both the treatments enhanced body weight, liver glycogen satisfied status once compared to the diabetic control. It have been concluded that Uraria picta leave extract, in adding to the antidiabetic action, too own antihyperlipidemic actions in the streptozotocininduced diabetic model.
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