EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia ,

ISSN 2394-3211

Impact Factor: 7.065

ICV - 79.57

Abstract

CASE OF SPINAL NEUROFIBROMA (SCHWANNOMA) IN PREGNANCY AT 36WEEKS

*Dr. Seema Dande, Dr. Sagar Shahane and Dr. Girish Thakre

ABSTRACT

Neurofibromas are the tumors of the nerve sheath or the layer of insulation that surrounds the nerve fibers. They arise from Schwann cells which produce the insulating sheath for all nerves outside the brain and spinal cord. Spinal neurofibromas are benign and slow growing. Surgery is the treatment of choice for symptomatic lesions. 5 to 10 percent of neurofibromas undergo malignant change which is indicated by rapid growth. The differential diagnosis include the spinal schwannoma and spinal meningioma. Neurofibromatosis type 1 is one of the most common genetic diseases following an autosomal dominant inheritance pattern. Neurofibromas have been noted to increase in size and number in up to 82 percent of pregnancies. This is due to the proliferative effect of estradiol (E2) and progesterone in tumor expressive hormone tumors.

Keywords: Pregnancy, Schwannoma, Estrogen, NeurofIbroma.

[Full Text Article] [Download Certificate]