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 ISSN 2394-3211

Impact Factor: 7.065

 ICV - 79.57



*Dr. Divya C.S., Dr. Manu K.N. and Dr. Aarti Patil


Objective – The objective of the study was to evaluate the efficacy and safety of non-hormonal combination therapy of Ayurveda formulations in females suffering from irregular menstrual cycles due to PCOS. Materials & Method – The study was an open-label, non-comparative, single centre, prospective, interventional clinical study. A total of 190 female patients suffering from PCOS (diagnosed by USG) between the age group of 15-40 years having complaints of irregular menstrual cycles were recruited in the study. Participants were advised to take combination therapy of two proprietary marketed products containing ingredients like Kanchanaar, Shatavari, Dashmool etc. (Myrah and Vamah Tablets) in a dose of 2 tablets twice daily with water for 6 months. Monthly follow up of participants was done to assess frequency of menstrual cycle, no of days of bleeding, quantity of bleeding and associated symptoms while USG was repeated at the end of the study. Results – Female participants of average age 23.05 ± 7.78 having PCOS over a period of 6.78 ± 3.45 months were recruited. A total of 137/190 participants (72.10%) reported of regular menstrual cycles at the end of 6 months. The No. of days of bleeding increased from 1.21 +/- 0.34 at baseline to 2.22 +/- 1.29 at the end of three months and 3.32 +/- 1.59 at the end of 6 months (p<0.05). Similarly quantity of bleeding also showed significant increase over the period of 3 and 6 months. USG was performed in 121 participants of which 45 subjects (37.19%) showed complete resolution, 48 subjects (39.66%) showed partial resolution while 27 participants (22.31%) did not show any change. None of the participants showed worsening in their condition. No adverse drug reaction was observed and the study products were well tolerated. Conclusion- Combination therapy of Ayurvedic tablets (Myrah & Vamah) was found to be effective in regularising menstrual cycles, improving overall menstrual flow and managing PCOS.

Keywords: PCOS, Myrah Tablets, Vamah Tablets.

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia