PLANT DERIVED VACCINES: A SYSTEMATIC REVIEW

Dr. Dewesh Kumar, Dr. Nusrat Noor, Dr. Vidya Sagar, Dr. Erum Yasmin and *Dr. Tanya Tanu

ABSTRACT

Vaccines provide immune protection against many human and animal diseases however unavailability and unaffordability of vaccines have caused a concern worldwide and attracted global attention towards production of more acceptable, cost effective, stable and safer vaccines. This paper aimed to review the potential of plant derived vaccines in making immunization ubiquitous with full acceptability and affordability with challenges in the path of its production and rolling out in immunization programs. This review was done with the help of search engines which included online electronic databases PUBMED/MEDLINE, EMBASE, SCIENCEDIRECT, Google Scholar and sources available in internet pertinent to my topic. On reviewing various papers, the information shared from the existing knowledge are highlighted here. In contrast to majority available vaccines, plants offer a right platform for the production of various vaccines having scalable potential. Plant derived vaccines (PDVs) are the result of novel approaches and advancement in immunology and biotechnology. Since 1992, many PDVs have already undergone different phases of clinical trials successfully. Not only vaccines are in pipeline for infectious agents but also for non-Communicable diseases like Diabetes Mellitus-I. Despite the limitations in its production and use, incessant efforts are being made in order to produce efficient vaccine for many human and animals related diseases owing to its great promises for future. Plants derived vaccine have opened new horizons and is encouraging us to think about the existing human problems and some of the least solved disease mysteries through newer and innovative approaches.

Keywords: Plant derived vaccines, transgenic, immunization.