THE EFFECT OF TOPICAL EPINASTINE 0.5MG/ML OPHTHALMIC SOLUTION ON OCULAR AND NASAL SYMPTOMS IN PATIENTS WITH SEASONAL ALLERGIC RHINO- CONJUNCTIVITIS

Osama Alwan*, MD. Noor Aladwan, MD. Firas Abu Muharib, MD. Neel Aladwan, MPharm, Dr. Esmat Iraifij, MD.

ABSTRACT

Aim: To evaluate the effect of epinastine 0.5mg/ml ophthalmic solution twice daily on ocular and nasal symptoms in patients with seasonal allergic rhino-conjunctivitis. Method: this retrospective study was conducted at the ophthalmology and otolaryngology clinic of King Hussein Medical Center. All patients who are diagnosed with seasonal allergic rhino-conjunctivitis and received only topical epinastine 0.5mg/ml ophthalmic solution twice daily were enrolled in the study. Patients who received systemic anti histamine or steroids or nasal preparation for allergic rhinitis were excluded from the study. Patients who were younger than 14 years of age were excluded from the study as well The patient’s records were reviewed regarding the improvement in nasal and ocular symptoms of allergic rhino-conjunctivitis including eye itching, eye redness, tearing, sneezing, Nose itching, and running nose after a period of 2 weeks, one month and three months after using the medication. The severity of symptoms was assessed subjectively by asking the patients to describe the symptoms as: absent, mild, moderate or sever which stand for scores of 0,1,2 and 3 respectively. The obtained results were analyzed using simple statistical analysis.

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