EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia ,

ISSN 2394-3211

Impact Factor: 7.065

ICV - 79.57

Abstract

IGY ANTIBODIES FROM EGGS DERIVED FROM DIFFERENT BIRD SPECIES AGAINST H5N1, H9N2 AND NDV

Aya Saed, Emad Elgendy and Madiha Salah Ibrahim*

ABSTRACT

IgY is the major antibody produced by the B cells of domestic birds. It is functionally comparable to mammalian IgG but differs in their structure. Because of its production in large amount and easy way, IgY becomes desirable to be used in both therapeutic and diagnostic approachs in chickens and other bird species. Here, we tested the neutralization ability and efficiency of IgY collected from different bird species, chicken, quail and duck, against avian influenza virus H5N1 and H9N2 as well as Newcastle disease virus. The results showed that IgY collected from different bird species were in high titer and can neutralize the viruses efficiently, exhibiting the ability of using the IgY antibodies as a prophylactic therapy against different viral diseases.

Keywords: H5N1, H9N2, NDV, IgY, Heamaglutination inhibition, ELIZA.

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