A CASE REPORT ON TELMISARTAN INDUCED HYPONATREMIA

Raveena Rajesh* and Dr. Sofy Binu

ABSTRACT

Hyponatremia is defined as a serum sodium concentration of less than 135 mEq/L. It is most often seen as a complication of some medical illnesses like heart failure, liver failure, kidney failure, pneumonia. The normal serum sodium concentration is 135- 145mEq/L. There are some drugs that leads to hyponatremia are ACE inhibitors, antibiotics like Trimethoprim- sulfamethoxazole, ciprofloxacin, cefoperazone sulbactam, antiarrhythmic, proton pump inhibitors. Telmisartan is an angiotensin receptor blocker used to treat hypertension which acts by inhibiting vasoconstrictor and aldosterone -secreting effect of angiotensin II. The common adverse effects are hyponatremia, hyperkalemia, upper respiratory tract infection, back pain, cough, impotence, increased sweating, palpitations, tachycardia, rash dermatitis. It is contraindicated to some other drugs like ramipril, aliskiren, elagolix.

Keywords: Hyponatremia, telmisartan, ARBs, hyperkalemia.