( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57



Pekova L.*, P. Parousheva and D. Petrov


We present a case of acute meningococcal sepsis in a 24-year old female. She presented with a 12 hours history of fever, asthenia, headache and vomiting. Just an hour before the admission a petechial rash on the lower extremities appeared. On admission there was a clinical manifestation of septic shock and cardiovascular collapse - temperature, RR 50/20, heart rate 140-160 per minute, respiratory rate 4 per minute. Her skin was greyish, cyanotic with a typical hemorrhagic-necrotic rash widely distributed over the lower extremities. Enlarged liver and spleen presented. The neurological examination revealed brisk tendon and periosted reflexes and mild signs of meningeal-radicular injury (MRI). Blood tests showed leukocytosis with a left shift, hemostasis disorders. The cerebrospinal fluid (CSF) changes were consisted with those of purulent bacterial meningitis. Microbiological blood and CSF tests proved N. meningitidis serogroup C. A provisional diagnosis of meningococcemia associated purpura fulminans (PF) was considered. Initial treatment with Medaxon and Penicillin with corticoids was started immediately. In the next days the patient’s condition deteriorated. The skin lesions progressed to involve the whole body, areas of hemorrhagic necrosis appeared. Auto-amputation of the dystal phalanges of II, III, IV and V toe of the right leg and the heel of the left leg occurred. The patient was discharged after a hospital stay of 28-day stay and transferred to the plastic surgery unit. Six years later after 16 reconstructive surgical procedures she was in invalid wheel-chair, a mother of a 2-year-old child.

Keywords: acute meningococcemia, adult patient, clinical course.

[Full Text Article]



  • New Issue Published

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    SEPTEMBER issue has been successfully launched on 1 SEPTEMBER 2023.

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    Its our Pleasure to Inform you that EJPMR Impact Factor has been increased from  5.804 to 6.222, due to high quality Publication at International Level

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database