EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia , 

 ISSN 2394-3211

Impact Factor: 7.065

 ICV - 79.57

Abstract

STEREOTACTIC BODY RADIOTHERAPY (SBRT) AND OLIGOMETASTATIC BLADDER CANCER: ABOUT A CASE AND REVIEW OF THE LITERATURE

Mane Maimouna*, Benkhaled Sofian, Van Gestel Dirk and Otte François-Xavier

ABSTRACT

Purpose: The term “oligo-metastasis” could be defined as a transition state between localized and widespread systemic cancer. In the uro-oncology field, very few cases of oligo-metastases of bladder cancer have been described, probably because of the high metastatic potential of muscle invasive bladder cancer. In fact, bladder cancer remains an important cause of morbidity and mortality, the latter being predominantly related to metastasis. Herein we report a case of an oligometastatic bladder cancer treated by SBRT and we review the literature on the treatment of this disease. Methods: We describe a case of pulmonary and lymph-node metastases of a high grade bladder cancer, which relapsed after surgical resection and chemotherapy. Results: After the patient was treated with SBRT at his 3 metastatic lesions, and dispite a transient episode of grade 2 dyspnea, he was clinically in good condition without any evidence of disease on PET-CT scan after 22 months. Conclusion: SBRT is an efficient metastasis-directed treatment, and may be an alternative to chemotherapy or surgery. However, our case highlights that SBRT although easily feasible is not without any risk and should be use with caution, especially outside recognize indications and clinical trials.

Keywords: SBRT, oligometastasis, bladder cancer.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia