EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia , 

 ISSN 2394-3211

Impact Factor: 7.065

 ICV - 79.57

Abstract

WHAT ?S EFFECT?VENESS ON THE HEART OF DRUGS USED ?N ALZHE?MER’S D?SEASE?

Hasan Ata Bolayir* and Asli Bolayir

ABSTRACT

Objective: The aim of this study was to retrospectively determine the Emergency or Cardiology department admission rates with cardiac complaints of the patients with Alzheimer’s disease(AD) and establish whether these rates changed between the patients who used acetylcholinesterase inhibitors (AchEI) and those who did not. Materials and Methods: This single-centered retrospective study included 605 patients who were diagnosed with AD between January 2010 and 2018. The patient group was separated to two subgroups according to the use of AChEIs. Results: Comparison of these two subgroups in terms of baseline demographic and clinical characteristics demonstrated that there was no significant difference between them(p>0.05). When these two groups were compared in terms of the ratio of myocardial infarction, angina pectoris, bradycardia, hypotension or serious arrhythmia identicated that there was no significant difference (respectively, p=0.96, p=0.87, p=0.12, p=0.23, p=0.17). Besides, there was no significant difference between two groups in terms of the ratio of cardiac causes of death,too(p=0.21). Conclusion: In this study, it was shown that there was no significant difference between the ratio of cardiac death and Cardiology and/ or Emergency department admission with cardiac complaints between patients with AD using AChEIs and those not using.

Keywords: Alzheimer’s disease, acetylcholinesterase inhibitors, myocardial infarction, bradycardia, angina pectoris, mortality.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia