EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia , 

 ISSN 2394-3211

Impact Factor: 7.065

 ICV - 79.57

Abstract

STUDY OF VITAMIN B12, FOLATE AND ADIPOKINES WITH RESPECT TO INSULIN RESISTANCE (IR) AND ANTHROPOMETRY (BIRTH WEIGHT AND BMI) IN CHILDREN (AGE 10 – 20 YEARS)

Thakre R. R.*, Abhang S. A. and Naik S. S.

ABSTRACT

Background: Childhood obesity is set to increase phenomenally in India in near future. Birth weight a reflection of maternal nutrition and fetal programming, which may predict the cause of obesity. Micronutrients (Vitamin B12, Folate) and Adipokines (adiponectin and leptin) also play an important role in development of insulin resistance and obesity. The aim of the study is to evaluate the combined effect of micronutrients and adipokines on insulin resistance in Indian school-going children in the age group of 10–20 years. This study also describes distribution of micronutrient concentrations and it’s interrelationship with birth weight, body mass index (BMI), and insulin resistance. Methods: A cross-sectional study involves a total of 200 school going children between the age group of 10-20 yrs. Fasting plasma glucose, insulin, adiponectin, leptin, Vitamin B12, and folate were measured for the school going children and birth weight was recorded. BMI body mass index was defined as weight (kg) divided by height (m) squared. Insulin resistance was assessed using the homeostasis model (HOMA-IR). Results: Birth weight was not related to folate concentration but inversely to leptin and insulin resistance. Obese Children had higher leptin, birth weight, insulin with lower folate, and adiponectin levels. Conclusion: Adipokines partially protect fat induced obesity. Leptin induces insulin resistance and inflammation. Insulin resistance, leptin, and adiponectin were associated with fat mass. Folate consumption protects from developing obesity and adiposity. However the relationship of birth weight and BMI with micronutrients and adipokines needs further evaluation.

Keywords: Adiponectin and Leptin, Vitamin B12, Folate, Birth weight, BMI, and Insulin resistance.


[Full Text Article] [Download Certificate]

Citation

  All Since 2019
 Citation  3086  2560
 h-index  18  17
 i10-index  64  44

INDEXING

NEWS & UPDATION

  • New Issue Published

    Its Our pleasure to inform you that, EJPMR 1 March 2024 Issue has been Published, Kindly check it on https://www.ejpmr.com/issue

  • EJPMR: MARCH ISSUE PUBLISHED

    MARCH 2024 issue has been successfully launched on MARCH 2024.

  • EJPMR New Impact Factor

    EJPMR Impact Factor has been Increased to 7.065 for Year 2024.

  • Index Copernicus Value

    EJPMR Received Index Copernicus Value 79.57, due to High Quality Publication in EJPMR at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • Article Invited for Publication

    Article are invited for publication in EJPMR Coming Issue

Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia