EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia , 

 ISSN 2394-3211

Impact Factor: 7.065

 ICV - 79.57

Abstract

ANTIOXIDANT EFFECTS OF SESAME SEED OIL AND THEIR IMPACT IN IMPROVING MALE FERTILITY OF NORMAL AND DIABETIC RATS

*Atef E. Abd El-Baky

ABSTRACT

Great efforts have been made to identify an ideal herb with strong and effective anti-metabolic effects on male fertility. The purpose of the present study was to investigate the antioxidant effects of sesame seed oil and their impact on reproductive parameters of diabetic rats. Materials and Methods: Rats were divided into four groups. 1st normal group, 2nd normal rats supplemented with oil enriched diet, 3rd diabetic group, 4th diabetic rats supplemented with oil enriched diet for eight weeks. Results: Sesame oil increased testosterone, sperm number and motility in both normal and diabetic groups. The normal rats supplemented with oil showing elevation in glutathione peroxidase(GPx) and (GSH) while malondialdehyde (MDA)level was decreased. Superoxide dismutase, GSH and GPx were decreased in diabetic group, but were increased with oil supplementation compared to diabetic group. MDA level was elevated in diabetic group compared with normal group. On the other hand, sesame oil supplementation ameliorated MDA level compared to diabetic group. Conclusions: Sesame oil has powerful antioxidant activity, which reflected on improved testosterone level, sperm production and sperm motility in both normal and diabetic groups, but was not effective in reducing plasma glucose level in diabetic group.

Keywords: Sesame seed; Testis; Sperm; Infertility; Diabetes mellitus; Antioxidant.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia