EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

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Abstract

DIAGNOSTIC YIELD AND SAFETY OF CT SCAN GUIDED TRANS THORACIC FINE NEEDLE ASPIRATION CYTOLOGY IN PERIPHERAL LUNG LESIONS

Dr. Poonam Salwan*, Dr. Sunil Wadhwa and Dr. Shalini Salwan

ABSTRACT

Aims and Objectives: To obtain a sample of tissue by CT scan guided FNAC for pathological (cytopathological and histopathological) and / or microbiological analysis and to evaluate its efficacy to reach a definitive diagnosis. Material and Methods: 60 patients comprising 48 males and 12 females between 14 to 85 years with lesions in the peripheral lung fields were subjected to CT guided transthoracic fine needle aspiration (FNA) for a definitive diagnosis of benign or malignant lesion or for microbiological analysis to establish the etiologic agent. The procedures were performed using the siemens somatom AR.C CT unit with 18-22 gauge needles. Smears and tissue sections were evaluated simultaneously to reach at a definite diagnosis. An immediate post biopsy scan along with an expiration PA chest radiograph after 2 hours, were obtained to detect the presence of pneumothorax. Results: The commonest lesions diagnosed were inflammatory 41.6% and most of them were non-specific. Among the specific infections, Nocardia was most commonly seen. The post renal transplant – immunocompromised patients were benefited by specific diagnosis in 7 out of 9 patients i.e 77.7%. Primary malignancies were detected in 19/60 patients i.e 31.6% cases. The most common type detected being Non-small cell carcinoma in 17 cases. Secondary deposits were seen in 2 patients. The FNAC showed an overall positivity of 76.6%. In our patients, pneumothorax was seen as a complication in 4 patients i.e. 6.6% only. Conclusion: Fine needle aspiration cytology (FNAC) has a good overall yield for diagnosis of focal radiographic lesions. It is safe, accurate, relatively non invasive and cost effective method of obtaining diagnosis.

Keywords: Fine needle sampling, Fine needle aspiration cytology (FNAC), CT-guided FNAC.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia