EFFECT OF CIGARETTE SMOKING ON WEIGHT OF HUMAN LENS

Dr. Syed Anzar Ahmed, Dr. Alvina Anzar, Dr. Amna Anzar, Dr. Imtiaz Ahmad, Osama Anzar and *Kisa Fatima Altaf

ABSTRACT

Background: The growth of lens of eye takes place throughout life due to addition of new cells from the single layer of cuboidal cells beneath the capsule and thus may remain exposed to influences like oxidative stress for longer period. Cigarette smoking leads to deposition of metals in smokers and even in their lenses, known to cause oxidative stress. The aim of study was to see the association of metal deposition due to cigarette smoking on weight/growth of lens. Materials & Methods: Total 100 patients having nuclear cataract including smokers and non-smokers were randomly selected from OPD of LRBT Hospital. After surgical extraction (ECCE) lenses were weighed by scientific balance and then copper, cadmium and lead concentrations were determined by Atomic Absorption Spectrophotometer. Result: Weight of Lens was found to be significantly lower in Smokers than Non-Smokers. Also Negative Correlation between Concentration of Metals and Weight of Lens was observed. Conclusion: The study is indicative of how smoking (air pollution) affects the cellular integrity and viability of lens of human eye. It emphasizes the importance of preventive measures by identifying the relationship of environmental pollution and increasing cases of different organ failures to improve the general health and economics of people.

Keywords: Smoking, Lens, Weight, Oxidative, Metals.